Thermo Fisher Scientific CD1C Monoclonal Antibody (OTI1H9), TrueMAB

Applications and Tested Dilution

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
When using this carrier-free antibody for conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

The CD1C gene encodes a member of the CD1 family of transmembrane glycoproteins, structurally related to MHC proteins, forming heterodimers with beta-2-microglobulin.
CD1 proteins present lipid and glycolipid antigens of self or microbial origin to T cells.
The human genome contains five CD1 family genes organized in a cluster on chromosome 1.
CD1 family members differ in localization and lipid ligand specificity.
The CD1C protein localizes to late endosomes and lysosomes via a tyrosine-based motif in its cytoplasmic tail and requires vesicular acidification to bind lipid antigens.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.