Thermo Fisher Scientific GALNT6 Polyclonal Antibody
GALNT6 단백질을 인식하는 Thermo Fisher의 rabbit polyclonal 항체로, WB, IHC(P), ICC/IF에 적합합니다. 인간 및 랫드 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로 단기 4°C, 장기 -20°C 보관 권장.
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- PA528064
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 30–518 of Human GALNT6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.79 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2545540 |
Product Specific Information
- Recommended positive controls: 293T, A431, H1299, Molt-4, PC-12
- Predicted reactivity: Mouse (92%), Rat (91%), Xenopus laevis (80%), Chicken (82%), Bovine (92%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes.
GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins.
They are characterized by:
- N-terminal transmembrane domain
- Stem region
- Lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif
- C-terminal ricin/lectin-like domain
GalNAc-Ts have different but overlapping substrate specificities and expression patterns.
The encoded protein glycosylates fibronectin peptide in vitro and is expressed in fibroblast cell lines, suggesting a role in the synthesis of oncofetal fibronectin.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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