Thermo Fisher Scientific Human Resistin Recombinant Protein
인간 Resistin 재조합 단백질로, E. coli에서 발현된 N-말단 His-tag 단백질입니다. Western blot 등 다양한 면역학적 실험의 양성 대조군으로 사용 가능하며, 고순도(>95%)로 정제되어 안정적인 결과를 제공합니다. 연구용으로만 사용됩니다.
- 카탈로그번호
- RP757xx (2개 옵션)
- 카테고리
- Protein
- 판매단위
- pk
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Thermo Fisher Scientific Human Resistin Recombinant Protein
Applications
- Western Blot (WB): Assay-dependent
- Control (Ctrl): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Expression System | E. coli |
| Amino Acid Sequence | Amino acids Ser17–Pro108 containing an N-terminal His-tag |
| Tag | His-tag |
| Molecular Weight | 14.2 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity | >95%, by SDS-PAGE under reducing conditions |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.14 mg/mL |
| Purification | Purified |
| Storage Buffer | 20 mM Tris-HCl, pH 8, with 5 mM EDTA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Product Specific Information
This product contains purified recombinant human Resistin protein with an N-terminal hexahistidine tag.
It may be used as a positive control in many immunological assays.
Target Information
Adipose tissue acts as an energy reserve and is tightly regulated. Adipocytes produce and secrete various physiologically important proteins such as lipoprotein lipase (LPL), leptin, Acrp30, perilipin, and resistin.
Resistin, also known as Adipocyte Secreted Factor (ADSF) and FIZZ3, is a cytokine secreted specifically by adipocytes. Although its function is not fully understood, it plays key paracrine roles and is implicated in type 2 diabetes.
Studies show that serum resistin levels are elevated in obese, diabetic mice, antagonizing insulin activity and inducing insulin resistance and glucose intolerance. Resistin gene expression requires C/EBP alpha, and coactivators CBP and p300 acetylate histones at the resistin promoter, activating chromatin for transcription. PPAR gamma and RXR ligands have been shown to downregulate resistin expression in adipocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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