Thermo Fisher Scientific ASH2L Polyclonal Antibody
Thermo Fisher Scientific의 ASH2L 폴리클로널 항체는 인간, 생쥐, 랫트에 반응하며 핵 내 단백질 ASH2L을 검출합니다. Western blot, IHC, Flow cytometry에 사용 가능하며, 고순도 친화 크로마토그래피로 정제된 액상 형태입니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:500
Flow Cytometry (Flow)
- Tested Dilution: 1:50–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within human ASH2L aa 575–628 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | TBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2913566 |
Product Specific Information
- Positive Control: Hela cell lysates, PC-12 cell lysates, mouse colon tissue, human breast carcinoma tissue, human colon tissue, Siha.
- Subcellular Location: Nucleus
Target Information
The human ASH2L gene encodes a 628 amino acid protein (isoform 1, ASH2L1) with a nuclear localization signal and PHD finger motif, functioning as a transcription regulator.
Predicted molecular weight: 68.7 kDa
Alternative splicing may produce isoforms at 60 kDa and 56.5 kDa.
Human ASH2L proteins share:
- 60% homology with Drosophila ash2 (developmental gene regulation)
- 90% homology with mouse ASH2L
Expression is predominant in adult heart, testis, and fetal lung/liver, with low levels in adult lung, liver, kidney, prostate, and leukocytes.
ASH2L is linked to hematopoiesis and certain leukemia types and may interact with beta-tubulin and beta-catenin.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-119994_ASH2L_Q9UBL3-1_Rabbit.svg, PA5-119994_ASH2L_Q9UBL3-1_Rabbit_PDP.jpeg)
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