Thermo Fisher Scientific Cyclin F Polyclonal Antibody
Cyclin F 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC/IF 등 다양한 응용에 적합합니다. 고순도 Affinity Chromatography로 정제되었으며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 인체 유래 Cyclin F 펩타이드(aa 752-786)를 면역원으로 사용합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | - |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CCNF (Accession P41002), corresponding to amino acid residues P752–L786 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818396 |
Product Specific Information
Antibody detects endogenous levels of total Cyclin F.
Target Information
This gene encodes a member of the cyclin family, which regulates cell cycle transitions through activation of cyclin-dependent protein kinases. Cyclin F also belongs to the F-box protein family, characterized by a 40 amino acid F-box motif. F-box proteins are components of the SCF ubiquitin ligase complex (SKP1–Cullin–F-box), functioning in phosphorylation-dependent ubiquitination. They are classified into three groups: Fbws (WD-40 domains), Fbls (leucine-rich repeats), and Fbxs (varied interaction modules or no recognizable motifs). Cyclin F belongs to the Fbxs class and was one of the first identified F-box proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: PA5-99463_Cyclin_F_P41002-1_Rabbit.svg, PA5-99463_Cyclin_F_P41002-1_Rabbit_PDP.jpeg)
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