Thermo Fisher Scientific IL-2 Polyclonal Antibody
Thermo Fisher Scientific의 IL-2 Polyclonal Antibody는 소 IL-2에 특이적인 염소 유래 IgG 항체로, WB, ICC/IF, ELISA 등 다양한 응용에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 높은 특이성과 낮은 교차 반응성을 제공합니다.
- 카탈로그번호
- PA546923
- 판매단위
- pk
카탈로그
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1 µg/mL |
| Immunocytochemistry (ICC/IF) | 5–15 µg/mL |
| ELISA (Detection) | 0.1–0.4 µg/mL |
| ELISA (Capture) | 0.2–0.8 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Bovine |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived recombinant bovine IL-2 (Ala21–Thr155) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609724 |
Product Specific Information
- In sandwich ELISAs, less than 0.2% cross-reactivity with recombinant IL-2 from human, mouse, rat, feline, canine, equine, cotton rat, and porcine sources is observed.
- Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
Interleukin 2 (IL-2) is an immuno-modulatory cytokine crucial for the proliferation of activated T cells and the differentiation of B cells, NK cells, monocytes, and macrophages.
IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric complex whose gamma chain is also shared by IL-4 and IL-7.
Expression of the IL-2 gene in mature thymocytes is monoallelic, representing a unique regulatory mechanism for gene expression.
Disruption of an IL-2-like gene in mice results in an ulcerative colitis-like disease, indicating its essential role in immune response regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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