Thermo Fisher Scientific N-Ras Polyclonal Antibody
Thermo Fisher Scientific의 N-Ras Polyclonal Antibody는 인간 및 마우스 시료에 반응하는 토끼 유래 IgG 항체입니다. Western blot에 최적화되어 있으며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 기반 완충액에 보관되며, 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested dilution: 1:500–1:3,000
- View 2 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Full length human N-Ras recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.41 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2546337 |
Product Specific Information
- Recommended positive control: mouse brain
- Predicted reactivity: Mouse (99%), Rat (99%), Zebrafish (90%), Xenopus laevis (92%), Dog (100%), Pig (100%), Chicken (96%), Bovine (100%), Guinea pig (99%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
NRAS (GTPase NRas) is a membrane-associated protein that cycles between the Golgi apparatus and plasma membrane. This process is regulated by palmitoylation and depalmitoylation via the ZDHHC9-GOLGA7 complex. NRAS possesses intrinsic GTPase activity, activated by GTPase activating proteins and inactivated by guanine nucleotide-exchange factors.
Mutations in NRAS are associated with juvenile myelomonocytic leukemia (JMML) and Noonan syndrome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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