Thermo Fisher Scientific RASGRP2 Polyclonal Antibody
RASGRP2 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot, IHC, ICC, IP 등 다양한 응용에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태. 인간 및 생쥐 반응성. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | - | View 1 publication |
| Immunoprecipitation (IP) | 1:100–1:500 | - |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 299–609 of Human RASGRP2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2546341 |
Product Specific Information
- Recommended positive controls: Raji, mouse liver
- Predicted reactivity: Mouse (96%), Rat (96%), Pig (97%), Rabbit (96%), Rhesus Monkey (99%), Bovine (95%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene is a brain-enriched nucleotide exchange factor containing an N-terminal GEF domain, two tandem EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain.
It activates small GTPases including RAS and RAP1/RAS3. Its nucleotide exchange activity is stimulated by calcium and diacylglycerol.
Three alternatively spliced transcript variants encoding the same protein have been identified.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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