Thermo Fisher Scientific HGF Polyclonal Antibody
HGF 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Western blot에 최적화되어 있습니다. 인간에 반응하며, 예측 반응종은 Mouse, Rat, Dog 등입니다. 액상 형태로 1 mg/mL 농도이며, 항원 친화 크로마토그래피로 정제되었습니다.
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Applications
Western Blot (WB)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the N-terminus region of human HGF |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792676 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (84%), Rat (85%), Dog (91%), Cat (91%), Rabbit (89%), Bovine (91%).
- Positive Control: Huh-7, HepG2.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Hepatocyte growth factor (HGF) regulates cell growth, motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the c-Met receptor. It is secreted by mesenchymal cells and acts as a multi-functional cytokine on epithelial cells. HGF stimulates mitogenesis, cell motility, and matrix invasion, playing a key role in angiogenesis, tumorogenesis, and tissue regeneration.
It is secreted as a single inactive polypeptide and cleaved into a 69-kDa alpha-chain and 34-kDa beta-chain linked by a disulfide bond to form the active heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but lacks protease activity. Alternative splicing produces multiple isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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