Thermo Fisher Scientific MPP2 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

Immunogen sequence:
MPVAATNSET AMQQVLDNLG SLPSATGAAE LDLIFLRGIM ESPIVRSLAK AHERLEETKL EAVRDNNLEL VQEILRDLAH VAEQSSTAAE LAHILQEPHF QSLLETHDSV ASKTYETPPP SPGLDPTFSN QPVPPDAVRM VGIRKTAGEH LGVTFRVEGG ELVIARILHG GMVAQQGLLH VGDIIKEVNG QPVGSDPRAL QELLRNASGS VILKILPSYQ EPHLPRQVFV

Positive Samples: HepG2, Mouse brain, Rat brain

Target Information

The MAGUK (membrane-associated guanylate kinase homologs) family of proteins contain multiple protein-binding domains and are involved in cell junction organization, tumor suppression, and signaling.
The MAGUK family is divided into four subfamilies: DLG-like, ZO1-like, p55-like, and LIN2-like.
MPP2 (membrane protein, palmitoylated 2), also known as MAGUK p55 subfamily member 2, discs large homolog 2 or DLG2, is a 576 amino acid protein belonging to the MAGUK family that exists as three alternatively spliced isoforms.
MPP2 contains one guanylate kinase-like domain, a PDZ (DHR) domain, two L27 domains, and a single SH3 domain.
The gene encoding MPP2 maps to the same segment of human chromosome 17 as MPP3, with whom MPP2 likely shares similar function and common structural organization.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.