Thermo Fisher Scientific NUP153 Recombinant Rabbit Monoclonal Antibody (8D4)
인간 NUP153 단백질을 인식하는 재조합 토끼 단클론 항체로, IHC, ICC/IF, ELISA에 사용 가능. HEK293 세포에서 발현되며, 고순도의 친화 크로마토그래피 정제 제품. 핵공복합체 연구 및 세포핵 단백질 분석에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:20–1:200 |
| ELISA | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 8D4 |
| Immunogen | A synthesized peptide derived from human Nup153 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_3092634 |
Target Information
Nuclear pore complexes regulate the transport of macromolecules between the nucleus and cytoplasm. They are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. Nucleoporins are glycoproteins found in nuclear pores and contain characteristic pentapeptide XFXFG repeats as well as O-linked N-acetylglucosamine residues oriented towards the cytoplasm.
The protein encoded by this gene has three distinct domains:
- A N-terminal region containing a pore targeting and an RNA-binding domain
- A central region containing multiple zinc finger motifs
- A C-terminal region containing multiple XFXFG repeats
Alternative splicing results in multiple transcript variants of this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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