Thermo Fisher Scientific CD80 Polyclonal Antibody
인간 CD80 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체입니다. IHC(P)에서 1:50~1:200 희석으로 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 기반 용액 형태로 제공되며, 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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- PA583990
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- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CD80 (Product #RP-103871) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2791142 |
Product Specific Information
Immunogen sequence:
YECVVLKYEK DAFKREHLAE VTLSVKADFP TPSISDFEIP TSNIRRIICS TSGGFPEPHL SWLENG
Target Information
CD80 (B7-1) and CD86 (B7-2) are ligands of the T-cell costimulatory molecule CD28 and the inhibitory receptor CTLA-4 (CD152). Both are expressed on professional antigen-presenting cells and are essential for T-cell activation.
CD80 is rapidly induced on activated B cells, EBV-transformed B cell lines, Burkitt’s lymphoma cell lines, and freshly isolated follicular B lymphoma cells, T cells, and monocytes.
The B-lymphocyte activation antigen B7-1 provides regulatory signals for T lymphocytes by binding to CD28 and CTLA4.
Diseases associated with CD80 dysfunction include gallbladder squamous cell carcinoma and myocarditis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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