Thermo Fisher Scientific ELOA3 Polyclonal Antibody

Thermo Fisher Scientific ELOA3 Polyclonal Antibody

제품 사양

Product Specific Information

Immunogen sequence: KTRKQAAKKV APLMAKAIRD YKGRFS

Target Information

The elongin (SIII) complex is composed of a transcriptionally active A subunit and two small regulatory subunits, B and C. This complex stimulates the transcription elongation rate of RNA polymerase II by suppressing time spent at template-encoded arresting sites along DNA.
Elongin A3, also known as RNA polymerase II transcription factor SIII subunit A3 and Transcription elongation factor B polypeptide 3C, is a 546 amino acid nuclear protein that functions as a general transcription elongation factor that increases RNA polymerase II transcription elongation and forms a stable complex with Elongin BC.
In contrast to Elongin A, transcriptional activity of Elongin A3 is not stimulated by Elongin BC. Elongin A3 contains one TFIIS N-terminal domain and is ubiquitously expressed in human tissue.

주의사항

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.