Thermo Fisher Scientific RBM15 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

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Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human RBM15. Recombinant protein control fragment (Product #RP-92572). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RBM15,uniProtId:Q96T37-1,ncbiNodeId:9606,antigenRange:264-378,antigenLength:977,antigenImageFileName:PA5-54089_RBM15_Q96T37-1_Rabbit.svg,antigenImageFileNamePDP:PA5-54089_RBM15_Q96T37-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.08 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2646367

Product Specific Information

Immunogen sequence: DTYPPSASVV GASVGGHRHP PGGGGGQRSL SPGGAALGYR DYRLQQLALG RLPPPPPPPL PRDLERERDY PFYERVRPAY SLEPRVGAGA GAAPFREVDE ISPEDDQRAN RTLFL

Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 94%.

Target Information

May function as an mRNA export factor, stimulating export and expression of RTE-containing mRNAs which are present in many retrotransposons that require to be exported prior to splicing. High affinity binding of pre-mRNA to RBM15 may allow targeting of the mRNP to the export helicase DBP5 in a manner that is independent of splicing-mediated NXF1 deposition, resulting in export prior to splicing. May be implicated in HOX gene regulation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.