Thermo Fisher Scientific MTA2 Polyclonal Antibody
MTA2 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western Blot 및 Immunohistochemistry에 사용 가능. HeLa cell lysate를 양성 대조군으로 권장하며, NuRD 복합체 관련 연구에 적합. 액상 형태로 -20°C 보관.
- 카탈로그번호
- PA112809
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Immunohistochemistry (IHC)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues 652–668 of human PID/MTA2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2146945 |
Product Specific Information
A suggested positive control for this product is HeLa cell lysate.
Target Information
This gene encodes a protein that is a component of the NuRD (nucleosome remodeling deacetylase) complex found in the nucleus of human cells. It is broadly expressed and strongly present in many tissues. The gene may belong to a small family encoding related proteins involved in transcriptional regulation, either directly or indirectly through chromatin remodeling. It is closely related to another family member associated with metastatic potential in certain carcinomas. These proteins share common domains including DNA-binding domains, a dimerization domain, and a methyltransferase-related domain. One known target of this gene product is p53; deacetylation of p53 correlates with loss of growth inhibition in transformed cells, linking this gene family to metastasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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