Thermo Fisher Scientific Phospho-MKK7 (Thr275) Polyclonal Antibody
Phospho-MKK7 (Thr275) 인산화 부위를 특이적으로 인식하는 Rabbit Polyclonal 항체. Western blot 및 Immunocytochemistry에 적합. Human, Mouse, Rat 반응성. 1 mg/mL 농도의 액상 형태로 제공되며, -20°C에서 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MAP2K7 (Accession O14733), corresponding to amino acid residues around phosphorylated Thr275. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2815945 |
Product Specific Information
This antibody detects endogenous levels of MKK7 only when phosphorylated at Thr275.
Target Information
The protein encoded by this gene is a dual specificity protein kinase belonging to the MAP kinase family. It specifically activates MAPK8/JNK1 and MAPK9/JNK2, and is phosphorylated and activated by MAP kinase kinases such as MAP3K1/MEKK1, MAP3K2/MEKK2, MAP3K3/MEKK5, and MAP4K2/GCK. This kinase mediates signal transduction in response to proinflammatory cytokines and environmental stress. Multiple alternatively spliced transcript variants exist, but only one has been confirmed.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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