Thermo Fisher Scientific CYP2E1 Polyclonal Antibody
CYP2E1 단백질을 인식하는 염소 유래 폴리클로날 항체로, Western blot 및 IHC(P) 실험에 적합합니다. 합성 펩타이드 면역원으로 제작되었으며, 0.5 mg/mL 농도의 액상 형태로 제공됩니다. 인간 시료 반응성이 높고, 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.05–0.2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3–5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (RKVIKNVAEVK) corresponding to the internal amino acids of CYP2E1 (aa 233–244) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10980259 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.
Target Information
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids.
This protein localizes to the endoplasmic reticulum and is induced by ethanol, diabetic state, and starvation. The enzyme metabolizes both endogenous substrates (ethanol, acetone, acetal) and exogenous substrates (benzene, carbon tetrachloride, ethylene glycol, nitrosamines).
Due to its broad substrate range, this enzyme may be involved in gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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