Thermo Fisher Scientific GPIHBP1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 50-151 of human GPIHBP1 (NP_8354662) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GPIHBP1,uniProtId:Q8IV16-1,ncbiNodeId:9606,antigenRange:50-151,antigenLength:184,antigenImageFileName:PA5-89108_GPIHBP1_Q8IV16-1_Rabbit.svg,antigenImageFileNamePDP:PA5-89108_GPIHBP1_Q8IV16-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.68 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2805360

Product Specific Information

Immunogen sequence: ETNRLPGGRS RVLLRCYTCK SLPRDERCNL TQNCSHGQTC TTLIAHGNTE SGLLTTHSTW CTDSCQPITK TVEGTQVTMT CCQSSLCNVP PWQSSRVQDP TG; Positive Samples: U-87MG, LO2; Cellular Location: Apical cell membrane, Basolateral cell membrane, Cell membrane, Extracellular side, GPI-anchor, Lipid-anchor, Peripheral membrane protein

Target Information

GPI-anchored HDL-binding protein 1 (Gpihbp1) is a novel protein that may be involved in the regulation of the delivery of fats to cells for energy and storage. Digested fats travel to the small intestine, where they are packaged into chylomicrons (particles filled with triglycerides). Chylomicrons then travel through the bloodstream and deliver triglycerides to tissues that are hungry for fuel or to adipose tissue for energy storage. Triglycerides are broken down or hydrolyzed by the enzyme lipoprotein lipase (LpL). The triglyceride breakdown products are then taken up and used by cells. Gpihbp1 is the molecule in capillaries that facilitates the capture of chylomicrons and facilitates the interaction with LpL. It has been shown that fats in the bloodstream are not readily metabolized in the absence of GPIHBP1.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.