Thermo Fisher Scientific FLT3 Polyclonal Antibody

Applications

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:100–1:1,000

Product Specifications

Product Specific Information

• Keep as concentrated solution.
• Predicted reactivity: Mouse (90%), Rat (89%), Dog (95%).
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

FLT3 is a tyrosine protein kinase belonging to the growth factor receptor tyrosine kinase family. Activation occurs upon binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, inducing homodimer formation and autophosphorylation. The activated receptor phosphorylates and activates multiple cytoplasmic effector molecules involved in apoptosis, proliferation, and differentiation of hematopoietic cells. Constitutive activation mutations are associated with acute myeloid leukemia and acute lymphoblastic leukemia.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.