Thermo Fisher Scientific DJ-1 Recombinant Rabbit Monoclonal Antibody (SN07-21)
DJ-1 단백질 검출용 재조합 토끼 단클론 항체로, Western blot, IHC, ICC, Flow cytometry에 적합. 높은 특이성과 재현성 제공. 단백질 A 정제, 액상 형태, 1 mg/mL 농도. 단기 4°C, 장기 -20°C 보관 권장.
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SN07-21 |
| Immunogen | Synthetic peptide within Human PARK7 (aa 11–60) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809582 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.
Advantages include:
- Improved specificity and sensitivity
- Lot-to-lot consistency
- Animal-origin-free formulation
- Broader immunoreactivity due to rabbit immune repertoire
Target Information
The DJ-1 gene product belongs to the peptidase C56 family. It acts as a positive regulator of androgen receptor-dependent transcription and may function as a redox-sensitive chaperone and oxidative stress sensor. It protects neurons against oxidative stress and cell death.
Mutations in this gene cause autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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