Thermo Fisher Scientific DYRK1A Polyclonal Antibody
Rabbit polyclonal antibody targeting human DYRK1A for WB and IHC applications. Recombinant protein immunogen, antigen affinity purified, and supplied in PBS with glycerol and sodium azide. Ideal for research on cell proliferation and Down syndrome-rela...
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human DYRK1A (control fragment: Product #RP-91462) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.10 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS (pH 7.2) with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C and avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2856210 |
Product Specific Information
Immunogen sequence:
VRQQFPAPLG WSGTEAPTQV TVETHPVQET TFHVAPQQNA LHHHHGNSSH HHHHHHHHHH HHGQQALGNR TRPRVYNSPT NSSSTQDSME VGHSHHSMTS LSSSTTSSST SSSSTG
Target Information
DYRK1A is a dual specificity kinase involved in cell proliferation. The gene for DYRK1A is located in the Down syndrome critical region of chromosome 21 and has been implicated in the pathogenesis of this disease. DYRK1A catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyruvate, the first and rate-limiting step in the phosphorylated pathway of serine biosynthesis, using NAD+/NADH as a cofactor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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