Thermo Fisher Scientific MAP2K3 Monoclonal Antibody (OTI3C8), TrueMAB
MAP2K3 단백질을 인식하는 Mouse 모노클로날 항체로, WB, IHC, ICC/IF 등 다양한 응용에 적합. 인간, 생쥐, 개, 랫트 반응성. 동결건조 형태로 제공되며, 고순도 친화 크로마토그래피 정제. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3C8 |
| Immunogen | Full length human recombinant protein of human MAP2K3 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
MAP2K3 (MEK3) is a dual-specificity protein kinase involved in cellular signal transduction pathways and necessary for glucose transporter expression. It phosphorylates and activates MAPK14/p38-MAPK, can be activated by insulin, and is linked to oncogenic transformation through RAS oncogene expression. Inhibition of MAP2K3 is associated with Yersinia pseudotuberculosis pathogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported for MEK3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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