
Thermo Fisher Scientific FAM131C Monoclonal Antibody (OTI6E2), TrueMAB
FAM131C 단백질을 인식하는 Mouse Monoclonal 항체로 Western blot 및 IHC(P)에서 검증됨. 고순도의 친화 크로마토그래피 정제 제품으로, 동결건조 형태로 제공되며 재구성 용이. 인간 시료에 반응하며 연구용으로 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6E2 |
| Immunogen | Full length human recombinant protein of human FAM131C produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The FAM131C gene encodes a member of the superoxide dismutase (SOD) protein family.
SODs are antioxidant enzymes that catalyze the conversion of superoxide radicals into hydrogen peroxide and oxygen, protecting tissues from oxidative stress.
Proteolytic processing of the encoded protein forms two distinct homotetramers with different affinities for the extracellular matrix (ECM):
- Type C subunit: intact protein, high affinity for heparin, ECM-anchored
- Type A subunit: cleaved form, low affinity for heparin, not ECM-bound
Mutations in this gene may be linked to increased heart disease risk.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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