Thermo Fisher Scientific TAF4 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:1,000–1:3,000
• Publications: [참조 없음]

Immunocytochemistry (ICC/IF)

• Tested Dilution: 1:100–1:500
• Publications: [참조 없음]

Product Specifications

Product Specific Information

Antibody detects endogenous levels of total TAF4.

Target Information

TAF II p105, also called TAF4B, is a cell-type specific transcriptional co-activator that is a component of the TFIID complex. It is expressed primarily in B cells and ovarian granulosa cells, and can interact with OCBA/POU2AF1 to activate B cell-specific octamer-dependent transcription.
Additionally, TAF II p105 plays an important role in co-activating the transcription factor NFκB and is essential for activation of anti-apoptotic genes such as TNFAIP3.
TAF II p135, also known as TAF4, TAF2C, TAF2C1, TAF4A or TAFII130, is a 1,085 amino acid subunit of TFIID that accelerates transcriptional activation triggered by thyroid hormone (TR) or retinoic acid (RA).
Localized to the nucleus, TAF II p135 contains one TAFH domain and is thought to bind to proteins that contain glutamine-rich domains, such as the transcription factor CREB.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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