Thermo Fisher Scientific PSMD8 Polyclonal Antibody
PSMD8 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 실험에 적합합니다. Human, Mouse, Rat에 반응하며, Protein A로 정제된 고품질 항체입니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Assay-dependent
Immunohistochemistry (Paraffin) (IHC (P))
- Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human PSMD8 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of two complexes: a 20S core and a 19S regulator.
The 20S core consists of four rings of 28 non-identical subunits — two rings of seven alpha subunits and two rings of seven beta subunits.
The 19S regulator includes a base (six ATPase subunits and two non-ATPase subunits) and a lid (up to ten non-ATPase subunits).
Proteasomes are distributed throughout eukaryotic cells and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway.
A modified form, the immunoproteasome, plays an essential role in processing class I MHC peptides.
This gene encodes a non-ATPase subunit of the 19S regulator, and a pseudogene has been identified on chromosome 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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