Thermo Fisher Scientific TRAP2 Polyclonal Antibody
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TRAP2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western Blot 및 IHC(P) 실험에 적합합니다. Human, Mouse, Rat에 반응하며 Protein A로 정제되었습니다. 1 mg/mL 농도의 액상 형태로, -20°C에서 보관합니다.
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Applications
- Western Blot (WB): Assay-dependent
- Immunohistochemistry (Paraffin) (IHC (P)): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human Proteasome 26S S2/TRAP2, amino acids 525–575 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
The 26S proteasome is a multicatalytic proteinase complex composed of a 20S core and a 19S regulator.
- The 20S core contains four rings of 28 non-identical subunits (two alpha and two beta rings).
- The 19S regulator includes a base (6 ATPase and 2 non-ATPase subunits) and a lid (up to 10 non-ATPase subunits).
Proteasomes are abundant in eukaryotic cells and cleave peptides in an ATP/ubiquitin-dependent, non-lysosomal pathway.
The immunoproteasome variant processes class I MHC peptides.
This gene encodes a non-ATPase subunit of the 19S regulator lid and may also participate in the TNF signaling pathway through interaction with the TNF type 1 receptor. A pseudogene is located on chromosome 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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