Thermo Fisher Scientific C1 inhibitor Monoclonal Antibody (8F3)

Applications

Tested Dilution

Publications

ELISA (ELISA)

Assay-dependent

-

Product Specifications

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

8F3

Immunogen

C1-inhibitor (C1INH) isolated from human plasma.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.98 mg/mL

Storage conditions

4° C, store in dark

Shipping conditions

Wet ice

RRID

AB_599215

Product Specific Information

HYB 288-05-02 is specific for human C1INH.

HYB 288-05-02 has been successfully used in ELISA procedures. HYB 288-05-02 reacts strongly with C1-INH. Strong reaction is seen with human serµm/plasma when tested in sandwich ELISA in combination with a polyclonal antibody against C1-INH, and in ELISA with C1-INH coated directly onto the microtiter well.

The HYB 288-05-02 immunogen is C1-inhibitor (C1INH) isolated from human plasma.

Epitope specificity of HYB 288-05-02 differs from that of HYB 288-02-02.

NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL

Target Information

C1-inhibitor (C1INH) functions as a regulator of the activation of the classical complement pathway and of the contact activation system of kinin generation and coagulation. Its primary biologically relevant target proteinases are C1r, C1s, coagulation factors XIa and XIIa, and plasma kallikrein. C1-inhibitor consists of one polypeptide chain and has a molecular mass of ~104 kDa. Serum concentration has been determined to 180 µg/mL.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.