Thermo Fisher Scientific Mouse CXCL13 (BLC/BCA-1) Recombinant Protein

Thermo Fisher Scientific Mouse CXCL13 (BLC/BCA-1) Recombinant Protein

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Reconstitution: Briefly centrifuge vial before opening. Reconstitute in sterile, distilled water to 0.1–1.0 mg/mL. Do not vortex. Store reconstituted solution at 2–8°C for up to 1 week. For long-term storage, dilute in buffer containing 0.1% BSA and store aliquots at -20°C to -80°C.
• Storage: Lyophilized protein is stable at room temperature for 1 month. For long-term storage, keep at -20°C. Aliquots with carrier protein are stable for ≥3 months at -20°C to -80°C. Avoid repeated freeze/thaw cycles.

Target Information

CXCL13 (also known as BCA-1 and Angie) is a small chemokine highly expressed in secondary lymphoid organs. It promotes migration of B lymphocytes (B-1 and B-2) to follicles in spleen, lymph nodes, and Peyer’s patches. Produced by macrophages, with high expression in large peritoneal macrophages, Kuppfer cells, and lung macrophages (CD11c+ and CD11c−).
The receptor for CXCL13 is CXCR5 (BLR-1), expressed on B cells, Tfh cells, and some memory T cells. CXCL13 is implicated in chronic lymphocytic leukemia (CCL) and serves as a plasma biomarker for germinal center activity and broadly neutralizing antibody generation against HIV.

For Research Use Only. Not for use in diagnostic procedures or resale without authorization.