Thermo Fisher Scientific Phospho-BRK (Tyr447) Polyclonal Antibody
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Applications
Tested Dilution
Publications
Western Blot (WB)
1:500-1:1,000
View 1 publication 1 publication
Immunocytochemistry (ICC/IF)
1:100-1:500
Product Specifications
Published species
Mouse
Host/Isotype
Rabbit / IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic phosphopeptide derived from human Breast Tumor Kinase around the phosphorylation site of Tyr447 (T-S-YP-E-N) if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
BRK,
uniProtId:
Q13882-1,
ncbiNodeId:
9606,
antigenRange:
447,
antigenLength:
451,
antigenImageFileName:
PA5-38413_BRK_Q13882-1_Rabbit.svg,
antigenImageFileNamePDP:
PA5-38413_BRK_Q13882-1_Rabbit_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
1 mg/mL
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2555014
Target Information
Breast tumor kinase (Brk) is a non-receptor protein tyrosine kinase expressed in over 60% of breast carcinoma tissue samples and breast tumor cell lines. Brk is 80% identity to Sik (Src-related intestinal kinase) and exhibits the features of a novel non-receptor tyrosine kinase, including amino terminal SH3 and SH2 domains. Low levels of Brk transcripts have been identified in some human breast tumor cell lines but not in normal breast tissue.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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