Thermo Fisher Scientific DCLK1 Recombinant Rabbit Monoclonal Antibody (ARC0984)
DCLK1 단백질을 인식하는 토끼 단클론 항체로, Western blot 및 ELISA에 적합합니다. 인간, 마우스, 랫트에 반응하며, HEK293 세포에서 발현된 재조합 항체입니다. 고순도 친화 크로마토그래피 정제 및 안정한 PBS/glycerol 저장 버퍼를 사용합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC0984 |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 600–700 of human DCAMKL1/DCLK1 (O15075) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.57 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849395 |
Product Specific Information
Immunogen sequence:
QILMGQVDFP SPYWDNVSDS AKELITMMLL VDVDQRFSAV QVLEHPWVND DGLPENEHQL SVAGKIKKHF NTGPKPNSTA AGVSVIATTA LDKERQVFRR R
Target Information
DCAMKL1 (DCLK1)
DCAMKL1, also known as doublecortin-like kinase 1, is a serine/threonine kinase containing two N-terminal doublecortin domains (which bind microtubules and regulate microtubule polymerization), a C-terminal serine/threonine protein kinase domain (homologous to Ca²⁺/calmodulin-dependent protein kinase), and a serine/proline-rich domain that mediates multiple protein-protein interactions.
DCAMKL1 is a microtubule-associated kinase capable of autophosphorylation and exhibits microtubule-polymerizing activity independent of its kinase function. It participates in neuronal migration, retrograde transport, neuronal apoptosis, and neurogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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