
Thermo Fisher Scientific DCTN3 Polyclonal Antibody
DCTN3 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC, ELISA 등 다양한 응용에 적합합니다. Human, Mouse, Rat에 반응하며, Protein A로 정제된 액상 항체입니다. -20°C 보관, 연구용 전용 제품입니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:400 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human DCTN3 (amino acids 41–150) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The DCTN3 gene encodes the smallest subunit of dynactin, a macromolecular complex composed of 10 subunits (22–150 kDa). Dynactin interacts with both microtubules and cytoplasmic dynein and plays a role in various cellular processes, including:
- ER-to-Golgi transport
- Centripetal movement of lysosomes and endosomes
- Spindle formation and cytokinesis
- Chromosome movement and nuclear positioning
- Axonogenesis
This subunit is primarily alpha-helical with minimal coiled-coil structure and binds directly to the largest dynactin subunit (p150). Alternative splicing generates two transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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