Thermo Fisher Scientific Aromatase Polyclonal Antibody
Aromatase 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF, ELISA에 적합. Human 및 Rat 반응성, 고순도 Affinity Chromatography 정제, -20°C 보관 안정성 제공.
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- PA5120182
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Thermo Fisher Scientific Aromatase Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 1–180 of human Aromatase (CYP19A1) (NP_000094.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2913754 |
Product Specific Information
- Positive test controls: HeLa, Rat brain
- Localization: Membrane, Peripheral membrane protein
Immunogen sequence:
MVLEMLNPIH YNITSIVPEA MPAATMPVLL LTGLFLLVWN YEGTSSIPGP GYCMGIGPLI SHGRFLWMGI GSACNYYNRV YGEFMRVWIS GEETLIISKS SSMFHIMKHN HYSSRFGSKL GLQCIGMHEK GIIFNNNPEL WKTTRPFFMK ALSGPGLVRM VTVCAESLKT HLDRLEEVTN
Target Information
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids. Aromatase localizes to the endoplasmic reticulum and catalyzes the final steps of estrogen biosynthesis through three successive hydroxylations of the A ring of androgens. Mutations can lead to altered aromatase activity, affecting estrogen-related physiological processes. Two transcript variants are expressed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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