Thermo Fisher Scientific ATR Polyclonal Antibody
ATR 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot 및 Immunoprecipitation에 적합. Human에 반응하며 Mouse에도 예측 반응. 항원 친화 크로마토그래피로 정제된 1 mg/mL 액상 제품으로, 4°C에서 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residues 1675 and 1725 of human Ataxia Telangiectasia and Rad3-related (ATR, UniProt ID: Q13535-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
Target Information
The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. It phosphorylates and activates several proteins involved in the inhibition of DNA replication and mitosis, and promotes DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene cause Seckel syndrome 1.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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