Thermo Fisher Scientific CDH4 Polyclonal Antibody

Applications

• Immunohistochemistry (Paraffin) (IHC (P)): 1:100–1:1,000

Product Specifications

Product Specific Information

• Predicted Reactivity: Human (100%), Chicken (91%)
• Store product as a concentrated solution.
• Centrifuge briefly prior to opening the vial.

Target Information

CDH4 is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region, and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Studies have shown stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines, providing the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.