Thermo Fisher Scientific CDKN2C Polyclonal Antibody
CDKN2C 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체입니다. Western blot 및 IHC(P) 실험에 적합하며, 인간·마우스·랫트 반응성을 보입니다. 항원 친화 크로마토그래피로 정제되었으며, 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
- 카탈로그번호
- PA578378
- 판매단위
- pk
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Thermo Fisher Scientific CDKN2C Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:500–1:3,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human p18 INK4c (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.33 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2735626 |
Product Specific Information
- Positive Control: Neuro2A, Raw264.7, C2C12, NIH-3T3
- Predicted Reactivity: Human (100%), Rat (88%), Rhesus Monkey (100%), Bovine (89%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene belongs to the INK4 family of cyclin-dependent kinase inhibitors. It interacts with CDK4 or CDK6 to prevent kinase activation, functioning as a cell growth regulator controlling G1 phase progression. Ectopic expression suppresses cell growth correlated with wild-type RB1 function. Knockout mouse studies suggest roles in spermatogenesis and tumorigenesis suppression. Two alternatively spliced transcript variants encoding identical proteins have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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