Thermo Fisher Scientific MST4 Polyclonal Antibody
MST4 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 인간, 마우스, 랫 등 다양한 종에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 보존제 없이 -20°C에서 보관합니다.
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Applications
- Western Blot (WB): 1:1,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the amino-terminal residues of human MST4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10981314 |
Product Specific Information
- It is not recommended to aliquot this antibody.
- This antibody is not cross-reactive with Mst1-3.
Target Information
MST4 is a member of the Ste20-like kinase family of serine/threonine kinases and is overexpressed during prostate cancer development. It belongs to the GCK group III family of kinases, containing an amino-terminal kinase domain and a carboxy-terminal regulatory domain that mediates homodimerization. MST4 localizes to the Golgi apparatus and is activated by binding to the Golgi matrix protein GM130. It can be cleaved by caspase-3 in vitro and may function in the apoptotic pathway. Several alternatively spliced transcript variants have been described, though the full-length nature of some remains undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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