Thermo Fisher Scientific Catalase Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature.
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use.

Anti-Catalase Antibody is an IgG fraction antibody purified from monospecific antiserum by a multi-step process including delipidation, salt fractionation, and ion exchange chromatography followed by extensive dialysis against the specified buffer.
Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum as well as purified and partially purified Catalase (Bovine liver). Cross-reactivity against Catalase from other tissues and species may occur but has not been specifically determined.

Target Information

Catalase is a homotetrameric heme-containing enzyme present within the matrix of all peroxisomes. It catalyzes the dismutation of hydrogen peroxide into water and oxygen.
Human catalase has the last four amino acids (-KANL) at the extreme C-terminus for peroxisome targeting. The monomer of human catalase is 61.3 kDa in molecular size.
Catalase is implicated in inflammation, mutagenesis, prevention of apoptosis, and stimulation of various tumors. Loss of catalase leads to the human genetic disease acatalasemia (Takahara’s disease).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.