Thermo Fisher Scientific CASQ1 Monoclonal Antibody (1D7)
Thermo Fisher Scientific의 CASQ1 단클론 항체(1D7)는 인간 Calsequestrin 단백질을 인식하는 Mouse IgG3 항체입니다. ELISA에 최적화되어 있으며, 액상 형태로 제공됩니다. 친화 크로마토그래피로 정제되었으며, 연구용으로만 사용 가능합니다.
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Applications
ELISA (ELISA)
- Tested Dilution: 1 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG3, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1D7 |
| Immunogen | CASQ1 (NP_001222, 29 a.a. ~130 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
QEGLDFPEYD GVDRVINVNA KNYKNVFKKY EVLALLYHEP PEDDKASQRQ FEMEELILEL AAQVLEDKGV GFGLVDSEKD AAVAKKLGLT EVDSMYVFKG DE
Target Information
The sarcoplasmic reticulum (SR) maintains intracellular calcium levels in cardiac and skeletal muscle by storing and releasing calcium. Among several SR calcium-binding proteins, calsequestrin is the most prominent. It sequesters calcium accumulated in the SR during muscle relaxation and is localized to the junctional and corbular SR. Calsequestrin localizes calcium near the junctional face of the terminal cisternae, enabling release into the cytosol via the ryanodine receptor. This protein is highly acidic, with large capacity and moderate to low affinity for calcium.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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