Thermo Fisher Scientific PSMB9 Recombinant Rabbit Monoclonal Antibody (23GB4110)
Recombinant rabbit monoclonal antibody targeting PSMB9 (Proteasome 20S LMP2), suitable for WB, ICC/IF, and Flow Cytometry. High specificity and purity via affinity chromatography. Provided in PBS with glycerol, ideal for research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunocytochemistry (ICC/IF) | 1:1,000 |
| Flow Cytometry (Flow) | 1:2,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB4110 |
| Immunogen | A synthesized peptide derived from Proteasome 20S LMP2 (180–219AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure composed of four rings of 28 non-identical subunits (two rings of seven alpha subunits and two rings of seven beta subunits). Proteasomes are distributed throughout eukaryotic cells at high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway.
An essential function of the immunoproteasome is the processing of class I MHC peptides. The PSMB9 gene encodes a member of the proteasome B-type family (T1B family), a 20S core beta subunit located in the class II region of the MHC. Proteolytic processing is required to generate a mature subunit.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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