Thermo Fisher Scientific Phospho-Chemokine Receptor 10 (Thr353) Polyclonal Antibody
Human CCR10 Thr353 인산화 부위를 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 면역세포 이동 및 피부 염증 연구에 활용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
- Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human CCR10 around the phosphorylation site of Thr353 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Dulbecco’s PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice (domestic); Dry ice (international) |
Target Information
Chemokines are small (approximately 8–14 kDa), mostly basic, structurally related molecules that regulate leukocyte trafficking through interactions with 7-transmembrane, G protein-coupled receptors.
They play key roles in immune system development, homeostasis, and function, and also influence CNS and endothelial cells in angiogenesis or angiostasis.
Chemokines are divided into two major subfamilies:
- CXC chemokines: first two conserved cysteines separated by one amino acid
- CC chemokines: first two conserved cysteines are adjacent
CCR10 is the receptor for CCL27, and CCR10–CCL27 interactions are involved in T cell–mediated skin inflammation.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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