Thermo Fisher Scientific IP3 receptor Polyclonal Antibody, Biotin
IP3 receptor를 표적으로 하는 Biotin 결합 폴리클로날 항체로, Western blot, ELISA, IP에 적합합니다. Rabbit IgG 기반으로 다양한 종에 반응하며, 고순도 친화성 크로마토그래피로 정제되었습니다. 세포 내 칼슘 신호 연구용으로 적합합니다.
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Thermo Fisher Scientific IP3 receptor Polyclonal Antibody, Biotin
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 100–150 on rat Inositol 1,4,5-triphosphate receptor type 2 protein |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | −20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate.
Involved in the regulation of epithelial secretion of electrolytes and fluid through interaction with AHCYL1.
Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by activation of CaM kinase II, leading to downstream apoptosis pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: ITPR1-BIOTIN_IP3_Receptor_1_P29994-1_Rabbit.svg)
(이미지: ITPR1-BIOTIN_IP3_Receptor_1_P29994-1_Rabbit_PDP.jpeg)
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