Thermo Fisher Scientific IP3 receptor Polyclonal Antibody
IP3 receptor에 특이적인 Rabbit Polyclonal Antibody로 다양한 종에 반응. WB, ELISA, IP 등 다중 응용 가능. 합성 펩타이드 항원 기반으로 제작되어 높은 특이성과 재현성을 제공. 연구용으로 세포 내 칼슘 신호 조절 연구에 적합.
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Thermo Fisher Scientific IP3 receptor Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Bovine, Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 100–150 on rat Inositol 1,4,5-triphosphate receptor type 2 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate.
Involved in the regulation of epithelial secretion of electrolytes and fluid through interaction with AHCYL1.
Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis via CaM kinase II activation, leading to downstream apoptosis pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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