Thermo Fisher Scientific APRIL Monoclonal Antibody (Sacha-1)
APRIL 단백질을 검출하는 Sacha-1 클론 Rat IgG2a 단일클론 항체입니다. IHC, ICC/IF, Flow Cytometry에 사용 가능하며 인간 및 생쥐 시료에서 APRIL을 인식합니다. 액상 형태로 제공되며 4°C 보관, 동결 금지 조건입니다.
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Thermo Fisher Scientific APRIL Monoclonal Antibody (Sacha-1)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (IHC) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | 5 µg/mL |
| Flow Cytometry (Flow) | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rat / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | Sacha-1 |
| Immunogen | Recombinant fusion protein of residues 105–250 of human APRIL fused to residues 16–108 of human headless ACRP30 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Wet ice |
| RRID | AB_2206548 |
Product Specific Information
MA1-21169 detects APRIL in Human and Mouse samples.
Target Information
Members of the TNF superfamily regulate immune responses and induce apoptosis. A novel member, APRIL (A Proliferation-Inducing Ligand), also known as TALL2 and TRDL1a, was identified in human and mouse. Two receptors for APRIL, TACI and BCMA, mediate its biological activity.
APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-κB, and induces cell death. APRIL, BlyS, and their receptors BCMA and TACI are implicated in autoimmune diseases and cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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