Thermo Fisher Scientific ATF1 Monoclonal Antibody (ATF1 2A9/8)
ATF1 단백질을 인식하는 Thermo Fisher의 단클론 항체로, Western blot 및 Immunoprecipitation에 사용 가능. 인간 및 효모 시료에 반응하며, 비결합형 액상 형태로 제공. 연구용으로 세포 성장 및 신호전달 관련 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
Immunoprecipitation (IP)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Yeast |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ATF1 2A9/8 |
| Immunogen | ATF1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.7 mg/mL |
| Purification | IgG fraction |
| Storage Buffer | PBS, pH 7.2 |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2227626 |
Product Specific Information
The predicted molecular weight of MA1-21313 is 60 kDa.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes an activating transcription factor belonging to the ATF subfamily and bZIP (basic-region leucine zipper) family. It regulates the expression of downstream target genes related to growth, survival, and other cellular activities.
Phosphorylation at serine 63 by kinases such as PKA, CaMK I/II, MSK, and CDK3 enhances its transactivation and transcriptional activities, contributing to cell transformation.
Chromosomal translocation involving this gene and FUS (chromosome 16) or EWSR1 (chromosome 22) can result in chimeric proteins associated with angiomatoid fibrous histiocytoma and clear cell sarcoma.
A pseudogene exists on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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