Thermo Fisher Scientific Phospho-PKC mu (Ser742) Polyclonal Antibody
Rabbit polyclonal antibody detecting phospho-PKC mu (Ser742). Suitable for Western blot in insect species. Unconjugated liquid form, stored at -20°C. For research use only, not for diagnostic applications.
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Applications
- Western Blot (WB)
Tested dilution: 1:1,000
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Product Specifications
| 항목 | 내용 |
|---|---|
| Published species | Insect |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | The antiserum was produced against a chemically synthesized phosphopeptide derived from a region of human PKCμ/PKD that contains serine 742. The sequence is conserved in mouse. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice (domestic); Wet or Dry ice (international) |
| RRID | AB_2533807 |
Target Information
The PKC family of serine/threonine kinases, including PRKCN (PKD3), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II, and gamma form the conventional family; their activities are Ca²⁺- and phospholipid-dependent. PKC mu activation is dependent on the phosphorylation of two activation loop sites, Ser744 and Ser748, via a PKC-dependent signaling pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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