Thermo Fisher Scientific TRAF2 Polyclonal Antibody
TRAF2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot에 최적화되어 있으며, Human, Mouse, Rat 등 다양한 종에 반응. 항원 친화 크로마토그래피로 정제된 액상 항체로, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to carboxy-terminal sequences of TRAF2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 126 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10979093 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
Tumor necrosis factor (TNF) receptor associated factors (TRAFs) are adaptor proteins linking TNF receptor superfamily members to signaling pathways, regulating cell death and stress responses. TRAF proteins share a conserved region enabling interactions with receptors and other TRAFs, activating diverse signal cascades.
TRAF2 and TRAF3 bind directly to CD40, a receptor involved in B cell immunity, and are essential for NF-kappa-B activation in mouse B lymphocytes. TRAF2, along with TRAF6, is required for CD40 signaling in non-hematopoietic cells and interacts with the lymphotoxin-beta receptor (LTβR) together with TRAF3 and apoptosis inhibitors cIAP1 and Smac.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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