Thermo Fisher Scientific CTHRC1 Polyclonal Antibody
CTHRC1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(P) 검증 완료. 인간, 생쥐, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 액상 항체로, 세포 이동 및 암 연구에 활용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | 19 amino acid peptide near the amino terminus of human CTHRC1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at –20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2554658 |
Product Specific Information
- Recommended positive control: Rat small intestine tissue lysate
- Detects only the larger isoform of CTHRC1 (two isoforms known)
Target Information
The Collagen triple helix repeat-containing protein (CTHRC1) is a glycosylated, secreted protein transiently expressed in the arterial wall in response to injury. It contributes to vascular remodeling by inhibiting collagen expression and promoting cell migration.
CTHRC1 is highly expressed in multiple human cancers, including pancreatic cancer, and plays a significant role in tumor progression and metastasis.
Overexpression can serve as an independent prognostic marker in gastric cancer. Mutations are associated with Barrett esophagus and esophageal adenocarcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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