Thermo Fisher Scientific EAAT3 (EAAC1) Polyclonal Antibody
상품 옵션 정보 | ||||||||
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
AGC-023-200UL | - | Thermo Fisher Scientific AGC-023-200UL EAAT3 (EAAC1) Polyclonal Antibody 200 ul pk | 재고문의 | pk | 1,125,000원 | - | 1,237,500원 | |
AGC-023-50UL | - | Thermo Fisher Scientific AGC-023-50UL EAAT3 (EAAC1) Polyclonal Antibody 50 ul pk | 재고문의 | pk | 927,000원 | - | 1,019,700원 |
다른 상품 둘러보기
Applications
Tested Dilution
Publications
Western Blot (WB)
1:400
Immunohistochemistry (Frozen) (IHC (F))
Assay-dependent
Product Specifications
Species Reactivity
Human, Mouse, Rat
Host/Isotype
Rabbit / IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)EPTILDNEDSDTKK, corresponding to amino acid residues487-500 of rat EAAT3, Intracellular, C-terminus if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
EAAC1,
uniProtId:
P51907-1,
ncbiNodeId:
10114,
antigenRange:
487-500,
antigenLength:
523,
antigenImageFileName:
AGC-023-200UL_EAAC1_P51907-1_Rabbit.svg,
antigenImageFileNamePDP:
AGC-023-200UL_EAAC1_P51907-1_Rabbit_PDP.jpeg,
sortOrder:
2}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Lyophilized
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 X g 5 min).
Target Information
L-glutamate is the major excitatory neurotransmitter in mammalian central nervous systems. To maintain glutamate levels below excitoxic levels, excess glutamate at excitatory synaptic clefts is removed by ion-coupled glutamate transporters. Four glutamate transporters have been identified: the sodium-dependent GLAST-1, GLT-1, EAAC-1 and the chloride-dependent EAAT-4. EAAC-1 is expressed in the CNS and also found in kidney and small intestine. Structural features of glutamate transporters are believed to include eight membrane-spanning alpha-helices and a loop-pore structure which is unique among secondary transporters but may resemble loop-pores found in ion channels. A second distinctive structural feature is the presence of a highly amphipathic membrane-spanning helix that provides a hydrophilic path through the membrane. Mice with homozygous deletions of the EAAC-1 transporter gene develop dicarboxylic aminoaciduria and display reduced spontaneous locomotor activity although no neurodegeneration was observed over a period of 12 months.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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