Thermo Fisher Scientific ACSL3 Polyclonal Antibody
ACSL3 단백질을 인식하는 Rabbit Polyclonal 항체로, 인간·생쥐·랫트 시료에 반응합니다. Western blot, IHC, ELISA에 사용 가능하며, 고순도 Affinity Chromatography 정제 제품입니다. 액상 형태로 -20°C 보관하며 연구용으로만 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 621–720 of human ACSL3 (NP_004448.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.53 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804743 |
Product Specific Information
- Positive Samples: HeLa, Mouse kidney
- Cellular Location: Endoplasmic reticulum membrane, microsome membrane, mitochondrion outer membrane, peroxisome membrane, single-pass type III membrane protein
- Immunogen sequence: CEMENEVLKV LSEAAISASL E
Target Information
An initial reaction in fatty acid metabolism in eukaryotic cells is activation of fatty acids catalyzed by acyl-CoA synthetase.
FACL3 (fatty acid CoA ligase, long-chain 3) is identified as a member of the acyl-CoA synthetase (ACS) family by PCR of rat brain cDNAs using primers based on the conserved region of the ACS protein.
The 720-amino acid rat protein preferentially utilizes myristate, laurate, arachidonate, and eicosapentaenoate, and is expressed primarily in brain.
The predicted 720-amino acid FACL3 human protein is 92% identical to that of rat.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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