Thermo Fisher Scientific TCL1A Polyclonal Antibody
TCL1A 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, 인간·마우스·랫트에서 반응합니다. Western blot 및 IHC(P) 실험에 적합하며, 고순도 Affinity Chromatography로 정제된 액상 형태입니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific TCL1A Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:500–1:2,000
- Immunohistochemistry (Paraffin) [IHC (P)]: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TCL1A (Accession P56279), corresponding to amino acid residues R60–L110 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851725 |
Product Specific Information
This antibody detects endogenous levels of total TCL1A.
Target Information
Overexpression of the TCL1 gene in humans has been implicated in the development of mature T-cell leukemia, where chromosomal rearrangements bring the TCL1 gene close to T-cell antigen receptor (TCR)-alpha or TCR-beta regulatory elements (Virgilio et al., 1998).
In normal T cells, TCL1 is expressed in CD4-/CD8- cells but not in later stages of differentiation.
TCL1 functions as a coactivator of the cell survival kinase AKT (Laine et al., 2000).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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